a room that has a brightly colored sofa and a huge piece of statement art... it's not something you see often, at least, not something done well. if you want to try this for yourself, i think yellow is the color to go with. it's bright and happy but also subdued enough that you can't easily overuse it.
try it with a piece of art and a sofa like this living room. or a pair of club chairs and a rug. or a table runner and dining chairs.